Serum antinuclear antibodies in progressive systemic sclerosis (scleroderma)

Antinuclear antibodies in systemic sclerosis

Serum amyloid A protein concentration in progressive systemic sclerosis (scleroderma).

Serum amyloid A protein (SAA) concentrations were determined in 62 patients with progressive systemic sclerosis (PSS). Forty-seven patients had normal or slightly elevated SAA levels (less than 1000 ng/ml = micrograms/l), while 15 patients had moderately to markedly elevated SAA levels, similar to those observed in active rheumatoid arthritis (RA) (greater than or equal to 1000 ng/ml = microgra...

Cellular immunity in progressive systemic sclerosis (scleroderma).

Progressive systemic sclerosis (PSS) or scleroderma is a multisystem disease which is usually grouped with other systemic rheumatic or connective tissue disorders. As a class these conditions are believed to result, at least in part, from aberrant immunity (Rodnan, 1971). Previous studies have demonstrated that a significant percentage of affected patients develop a spectrum of autoantibodies, ...

Antinuclear antibodies in patients with scleroderma (systemic sclerosis) and in their blood relatives and spouses.

OBJECTIVE To test the postulate that there is a higher prevalence of antinuclear antibodies (ANAs) in serum samples from blood relatives and from spouses of patients with scleroderma than in control samples, and that this provides evidence for both genetic and environmental factors influencing autoimmunity in scleroderma. METHOD Testing for ANAs was performed on 58 patients with scleroderma, ...

Antinuclear antibodies associated with pulmonary involvement in systemic sclerosis.

In response to Dr. Homasson, my comments are as follows: 1) Mv paper is about a personal experience with laser bronchoscopy Ofll\ 2) In the introductii)n, I mentioned a statenient by Dr. Shapshav drawn from reference 1 of my paper. 3) I have flO personal experience with that technique and therefore I am unable to judge Dr. Honiasson’s letter. I think Dr. Shapshay or Dr. Sanderson, who initiated...